Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities
Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities
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DOI：
10.1007/s00125-006-0503-1
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发表时间：
2007-02-01
期刊：
影响因子：
8.2
通讯作者：
Xiang, K. S.
中科院分区：
文献类型：
--
作者：
Jia, W. P.;Pang, C.;Xiang, K. S.
目的/假设估计患病率和发病率的糖尿病和糖调节受损（IGR）在中国人群年龄20-94 years.Subjects和方法A组的5,628名随机选择的成年人，年龄20-94岁，生活在华阳和曹杨社区在上海，中国，进行了调查，在1998年和2001年之间。2002- 2004年期间，对2 666名受试者进行了跟踪。结果根据2000年中国人口普查数据，基线时糖尿病和IGR的年龄标准化患病率分别为6.87%和8.53%。超过五分之二的糖尿病患者未被诊断出来。年龄校正的糖尿病和IGR患病率随年龄增加而增加。男性高血压、血脂异常和超重的年龄校正患病率显著高于女性（p < 0.001）。糖尿病和IGR的3年累积发病率分别为4.96%和11.10%。IGR受试者患糖尿病的相对风险显着高于NGT受试者（p < 0.001）。结论/解释过去几十年来，糖尿病或IGR的患病率和发生率急剧增加，尤其是在年轻年龄组中。很大一部分病例未得到诊断。我们强烈建议应实施以人群为基础的糖尿病筛查计划，并推广到年轻人。
Aims/hypothesis To estimate the prevalence and incidence of diabetes mellitus and impaired glucose regulation (IGR) in a Chinese population aged 20-94 years.Subjects and methods A group of 5,628 randomly selected adults, aged 20-94 years, living in the Huayang and Caoyang communities in Shanghai, China, were investigated between 1998 and 2001. During 2002-04, 2,666 subjects were followed up. All the participants underwent anthropometric measurements, blood biochemical analyses and a 75-g OGTT.Results Based on the 2000 census data of China, the age-standardised prevalences were 6.87% for diabetes and 8.53% for IGR at baseline. More than two in five cases with diabetes were undiagnosed. The age-adjusted prevalence of diabetes and IGR increased with age. The age-adjusted prevalences of hypertension, dyslipidaemia and overweight in males were significantly higher (p < 0.001) than in females. The 3-year cumulative incidence rates of diabetes and IGR were 4.96 and 11.10%, respectively. The relative risk of developing diabetes was significantly higher in subjects with IGR than in subjects with NGT (p < 0.001).Conclusions/interpretation The prevalence and incidence rates for diabetes or IGR have increased dramatically over the last decades, especially in younger age groups. A large proportion of cases are undiagnosed. We strongly recommend that population-based diabetes screening programmes should be implemented and generalised for younger people.