Multi-Responsive Supramolecular Double Hydrophilic Diblock Copolymer Driven by Host-Guest Inclusion Complexation between β-Cyclodextrin and Adamantyl Moieties
Multi-Responsive Supramolecular Double Hydrophilic Diblock Copolymer Driven by Host-Guest Inclusion Complexation between β-Cyclodextrin and Adamantyl Moieties
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DOI：
10.1002/macp.200900279
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发表时间：
2009-12-18
影响因子：
2.5
通讯作者：
Liu, Shiyong
中科院分区：
文献类型：
--
作者：
Liu, Hao;Zhang, Yanfeng;Liu, Shiyong
采用原子转移自由基聚合（ATRP）和点击化学相结合的方法合成了结构明确的端部β - cd聚n -异丙基丙烯酰胺（β - cd - pnipam）。此外，以含金刚烷的引发剂为原料，采用ATRP法合成了端部为金刚烷基的聚(2-（二乙基氨基）甲基丙烯酸乙酯（Ad-PDEA）。β - cd和金刚烷基之间的主客体包合作用驱动β - cd - pnipam和Ad-PDEA形成超分子双亲水嵌段共聚物（DHBC）。所制得的超分子PNIPAM-b-PDEA双嵌段共聚物通过对溶液pH和温度的双重作用，在水溶液中表现出有趣的多响应和可逆的胶束到囊泡转变行为。
Well-defined beta-CD-terminated poly(N-isopropylacrylamide) (beta-CD-PNIPAM) was synthesized via a combination of atom transfer radical polymerization (ATRP) and click chemistry. Moreover, adamantyl-terminated poly(2-(diethylamino)ethyl methacrylate) (Ad-PDEA) was synthesized by ATRP using an adamantane-containing initiator. Host-guest inclusion complexation between beta-CD and adamantyl moieties drives the formation of supramolecular double hydrophilic block copolymers (DHBC) from beta-CD-PNIPAM and Ad-PDEA. The obtained supramolecular PNIPAM-b-PDEA diblock copolymer exhibits intriguing multi-responsive and reversible micelle-to-vesicle transition behavior in aqueous solution by dually playing with solution pH and temperatures.