Oligosaccharides:: application in infant food
Oligosaccharides:: application in infant food
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DOI：
10.1016/s0378-3782(01)00202-x
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发表时间：
2001-11-01
影响因子：
2.5
通讯作者：
Santamaría-Orleans, A
中科院分区：
文献类型：
--
作者：
Rivero-Urgëll, M;Santamaría-Orleans, A
低聚果糖是母乳中存在的约130种化合物的复杂混合物。研究表明，人乳低聚糖可诱导母乳喂养婴儿结肠植物群中的双歧杆菌数量增加，同时由于其生物合成活性，致病性潜在细菌数量显著减少。复合寡糖作为竞争性受体，具有抑制病原体与细胞表面结合的能力。它们与降低感染和腹泻的风险以及改善免疫系统反应有关。由于其发酵引起的肠道pH值的降低，低聚糖引起植物群病原体的减少，双歧杆菌的增加和矿物质的可用性的增加。在食品工业中，低聚果糖和低聚半乳糖等简单低聚糖被用作生物合成低聚糖，一些婴儿产品含有它们，希望这可能提供母乳中低聚糖的一些益处。本文综述了低聚糖的特性、有益作用及其在食品工业中的应用。在成人中，一些低聚糖的益处已在几项临床试验中得到证实，但在婴儿中，需要进行更多的基础研究，以确定这些成分的代谢作用和每日摄入量与生物合成活性。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Oligosaccharides are a complex mixture of approximately 130 compounds present in human milk. It has been shown that human milk, oligosaccharides induce an increase in the number of bifidobacteria of colonic flora in breast-fed infants, accompanied with a significant reduction in the number of pathogenic potential bacteria, due to their bifidogenic activity. Complex oligosaccharides have the capacity of inhibiting the binding of pathogens to cell surface because they act as competitive receptors. They are associated with a lower risk of inflections and diarrhoea and an improvement of the immune system response. Due to the decrease of the pH intestinal caused by, their fermentation, oligosaccharides provoke a reduction of the flora pathogens, an increase of bifidobacteria and an increase of the availability of minerals. In the food industry, simple oligosaccharides such as fructooligosaccharides and galactooligosaccharides are used as bifidogenic oligosaccharides and some infant products contain them in the hope that this might provide some of the benefits attributed to oligosaccharides in human milk. This paper reviews characteristics of oligosaccharides, their beneficial effects and use of oligosaccharides in the food industry. In adults, the benefits of some of the oligosaccharides have been established in several clinical trials, but in infants more fundamental research is needed to establish the metabolic role of these components and the daily intake with bifidogenic activity. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.