The specificity of neutralizing antibodies to feline leukaemia viruses
The specificity of neutralizing antibodies to feline leukaemia viruses
复制标题
猫白血病病毒中和抗体的特异性
DOI:
10.1002/ijc.2910210615
复制
发表时间:
1978
影响因子:
6.4
通讯作者:
O. Jarrett
中科院分区:
文献类型:
--
作者:
P. Russell;O. Jarrett
Feline leukaemia viruses (FeLV) of subgroups A (FeLV‐A), B (FeLV‐B) and C (FeLV‐C) were examined by neutralization. The FeLV‐A isolates were monotypic. By contrast, there was antigenic variation within subgroups B and C. There was also considerable cross‐reactivity between subgroups. Thus, FeLV‐A viruses showed weak cross‐reactivity to the standard FeLV‐C isolate; four of the subgroup B viruses were identical and cross‐reacted with the standard FeLV‐C, but not with FeLV‐A or the fifth FeLV‐B, and this latter virus weakly cross‐reacted with FeLV‐A but not with the FeLV‐C; within subgroup C, one virus was indistinguishable from the standard FeLV‐C strain but the other two were very similar to FeLV‐A. Therefore, subgroup classification based on interference did not altogether correspond with neutralizing behaviour for subgroups B and C.