Malaria Vaccine: A Future Hope to Curtail the Global Malaria Burden
Malaria Vaccine: A Future Hope to Curtail the Global Malaria Burden
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DOI：
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发表时间：
2014-05
影响因子：
2.1
通讯作者：
Kaliyaperumal Karunamoorthi
中科院分区：
文献类型：
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作者：
Kaliyaperumal Karunamoorthi
据估计，世界上近一半的人口面临感染疟疾的风险，撒哈拉以南非洲是最危险的地区。现有的前线疟疾控制干预措施不仅昂贵，而且由于出现杀虫剂和抗药性而变得无效。它呼吁在潜在和可靠的疫苗作为额外工具方面采取一种创新的方法。几个世纪以来，公共卫生专家一直积极致力于研制安全、负担得起和有潜力的疟疾疫苗，因此也取得了显著的成就。然而，需要立即和有效地指出许多挑战，以设计出理想的预防性疟疾疫苗。因此，国际社会要想在不久的将来建立一个没有疟疾的世界，还需要等待相当长的时间。
It has been estimated that nearly half of the world's population is at the risk of contracting malaria with sub Saharan Africa being the most risky area. The existing frontline malaria control interventions are not only expensive but also become ineffective owing to the emergence of insecticide and drug resistance. It calls for an innovative approach in terms of potential and reliable vaccine as an additional tool. Over centuries, the public health experts have been actively engaged to formulate a safe, affordable and potential malaria vaccine and accordingly a notable achievement has also been attained. However, many challenges are required to be flagged immediately and effectively to devise an ideal prophylactic malaria vaccine. Therefore, the global community has to remain waiting quite a few more years to build a wannabe malaria-free world in the near future.