Analysing the complexation of amino acids and peptides with β‐cyciodextrin using electrospray ionization mass spectrometry
Analysing the complexation of amino acids and peptides with β‐cyciodextrin using electrospray ionization mass spectrometry
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使用电喷雾电离质谱分析氨基酸和肽与 β-环糊精的络合
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
M. Saunders
中科院分区：
文献类型：
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作者：
P. Camilleri;N. Haskins;A. New;M. Saunders
用电喷雾电离质谱法证实了环糊精与含有芳香酸残基的多肽之间形成非共价结合的包合物。这一初步研究表明，苯丙氨酸和色氨酸残基可以与s-环糊精形成1：1的复合物，而没有证据表明酪氨酸残基可以形成这种复合物。缓激肽含有两个苯丙氨酸残基，形成1：1和1：2复合物。
The formation of non-covalently bound inclusion complexes between s-cyclodextrin and peptides containing aromatic acid residues has been confirmed by elcctrospray ionization mass spectrometry. This preliminary study has indicated that phenylalanine and tryptophan residues can form 1:1 complexes with s-cyclodextrin whereas no evidence for such a complex could be found for tyrosine residues. Bradykinin, which contains two phenylalanine residues, formed both 1:1 and 1:2 complexes.