Abdominal Pain Is a Frequent Symptom of Gastroparesis
Abdominal Pain Is a Frequent Symptom of Gastroparesis
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DOI：
10.1016/j.cgh.2010.04.027
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发表时间：
2010-08-01
影响因子：
12.6
通讯作者：
Parkman, Henry P.
中科院分区：
文献类型：
--
作者：
Cherian, Dinu;Sachdeva, Priyanka;Parkman, Henry P.
背景与目的：虽然胃轻瘫（GP）最常见的症状是恶心和呕吐，但患者也报告腹痛。我们的目的是确定GP腹痛的患病率、严重程度和质量，并将腹痛与胃排空（GE）和生活质量相关联。方法：假定患有GP的患者接受了4小时GE造影和上消化道内窥镜检查，并完成了以下胃肠道症状患者评估（上消化道症状严重程度指数的患者评估），腹痛问卷结果：研究组包括68例患者，女性58人; 10例男性），GE延迟（18例糖尿病性胃轻瘫[DG]和50例特发性胃轻瘫[IG]）90%的患者存在腹痛（89% DG，90% IG），96%出现恶心（100%DG，IG）腹痛为上腹部43%，脐部13%，43%每天疼痛，38%持续疼痛，常由进食引起（72%），夜间（74%），干扰睡眠（66%）。根据上消化道症状严重程度指数的患者评估，症状严重程度排序为腹胀（3 8 ± 0 2），腹胀（3 6 ± 0 2）。恶心（3 6 ± 0 2）、上腹部不适（3 3 ± 0 2）、上腹痛（3 0 ± 0 2）、呕吐（2 2 ± 0 2）。腹痛程度与胃排空率无相关性，但与生活质量有中度相关性。腹痛与生活质量受损相关，但与GE无关。
BACKGROUND & AIMS: Although the most commonly recognized symptoms of gastroparesis (GP) are nausea and vomiting, patients also report abdominal pain We aimed to define the prevalence, severity, and quality of abdominal pain in GP and to correlate abdominal pain with gastric emptying (GE) and quality of life. METHODS: Patients presumed to have GP underwent 4-hour GE scintigraphy and upper endoscopy examinations and completed the following patient assessments of gastrointestinal symptoms (Patient Assessment of Upper Gastrointestinal Symptom Severity Index), abdominal pain questionnaires (Short-Form of the McGill Pain Questionnaire), and quality-of-life questionnaires RESULTS: The study group consisted of 68 patients (58 female; 10 male) with delayed GE (18 diabetic gastroparesis [DG] and 50 idiopathic gastroparesis [IG]) Abdominal pain was present in 90% of patients (89% DG, 90% IG) and nausea was present in 96% (100% DG, 94% IG) Abdominal pain was epigastric in 43% and umbilical in 13% Pain occurred daily in 43% and was constant in 38% Pain often was induced by eating (72%), was nocturnal (74%), and interfered with sleep (66%) Severity ranking of symptoms based on the Patient Assessment of Upper Gastrointestinal Symptom Severity Index was as follows abdominal fullness (3 8 +/- 0 2), bloating (3 6 +/- 0 2). nausea (3 6 +/- 0 2), upper abdominal discomfort (3 3 +/- 0 2), upper abdominal pain (3 0 +/- 0 2), and vomiting (2 2 +/- 0 2) Abdominal pain severity did not correlate with GE, but had moderate correlation with quality of life CONCLUSIONS: Abdominal pain is a frequent symptom in patients with GP, comparable with nausea and vomiting. Abdominal pain correlates with impaired quality of life but not with GE.