Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.
Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.
复制标题
经过基因工程改造后分泌白细胞介素 12 的成纤维细胞可以抑制肿瘤生长,并在体内诱导针对小鼠黑色素瘤的抗肿瘤免疫。
作者:
Tahara,H;Zeh3rd,HJ;Storkus,WJ;Pappo,I;Watkins,SC;Gubler,U;Wolf,SF;Robbins,PD;Lotze,MT