Archaeal proviruses TKV4 and MVV extend the PRD1-adenovirus lineage to the phylum Euryarchaeota
Archaeal proviruses TKV4 and MVV extend the PRD1-adenovirus lineage to the phylum Euryarchaeota
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DOI：
10.1016/j.virol.2008.01.043
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发表时间：
2008-05-25
期刊：
影响因子：
3.7
通讯作者：
Bamford, Dennis H.
中科院分区：
文献类型：
--
作者：
Krupovic, Mart;Bamford, Dennis H.
随着病毒结构数据的积累，预测感染不同生命领域宿主的病毒具有共同起源的病毒谱系假说得到了更多的支持。一种这样的谱系是PRD 1-腺病毒谱系，其将具有大面和双β桶三聚体外壳蛋白的二十面体dsDNA病毒联合起来。这一谱系以感染细菌和真核生物的许多病毒为代表。然而，只有一个成员的血统，Sulfolobtts turreted二十面体病毒，感染crenarcheal主机，已被确定在域degenea。在这项研究中，我们描述了两种古细菌前病毒（TKV 4和MVV）的基因组序列，它们分别整合到广古细菌物种小田卡拉嗜热球菌KOD 1和伏特甲烷球菌A3的tRNA基因的5 '和3 '远端区域。生物信息学方法允许将TKV 4和MVV置于PRD 1-腺病毒谱系中，从而将谱系扩展到第二古菌门广古菌。(c)2008年爱思唯尔公司All rights reserved.
The viral lineage hypothesis predicting a common origin for viruses that infect hosts residing in different domains of life gains more support as data on viral structures accumulates. One such lineage is the PRD1-adenovirus lineage, which unites icosahedral dsDNA viruses with large facets and a double beta-barrel trimer coat protein. This lineage is represented by a number of viruses infecting bacteria and eukaryotes. However, only one member of the lineage, Sulfolobtts turreted icosahedral virus, infecting a crenarchaeal host, has been identified in the domain Archaea. In this study we characterize the genomic sequences of two archaeal proviruses, TKV4 and MVV, integrated into the 5 '- and 3 '-distal regions of tRNA genes of the euryarchaeal species Thermococcus kodakaraensis KOD1 and Methanococcus voltae A3, respectively. Bioinformatic approaches allowed placement of TKV4 and MVV into the PRD1-adenovirus lineage, thus extending the lineage to the second archaeal phylum, Euryarchaeota. (c) 2008 Elsevier Inc. All rights reserved.