Alcohol drinking and breast cancer risk: An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Alcohol drinking and breast cancer risk: An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
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DOI：
10.1093/jjco/hym062
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发表时间：
2007-08-01
影响因子：
2.4
通讯作者：
Tsugane, Shoichiro
中科院分区：
文献类型：
--
作者：
Nagata, Chisato;Mizoue, Tetsuya;Tsugane, Shoichiro
背景：我们回顾了日本人群中饮酒与乳腺癌的流行病学研究。这份报告是一系列的文章，我们的研究小组评估现有的证据之间的关联与健康有关的生活方式和cancer.Methods：原始数据从MEDLINE检索PubMed或从Ichushi数据库的搜索，辅以人工检索。协会的评估是基于证据的强度和关联的程度，连同生物学的可接受性，如以前评估的国际癌症研究机构onCancer.Results：三个队列研究和八个病例对照研究确定。在队列研究中，关于饮酒和乳腺癌风险的结果不一致。一个显着的正相关，但另一个显示出非显着的负相关。在八项病例对照研究中，两项研究分别显示，每天饮酒和饮酒量较高的妇女的风险显著增加。实验研究已经支持了饮酒和乳腺癌risk.Conclusion之间的正相关的生物可接受性：我们得出结论，饮酒和乳腺癌风险之间的关联的流行病学证据仍然不足的数量和方法学质量的研究在日本人口。
Background: We reviewed epidemiological studies on alcohol drinking and breast cancer among the Japanese population. This report is one among a series of articles by our research group evaluating the existing evidence concerning the association between health-related lifestyles and cancer.Methods: Original data were obtained from MEDLINE searches using PubMed or from searches of the Ichushi database, complemented with manual searches. Evaluation of associations was based on the strength of evidence and the magnitude of association, together with biological plausibility as previously evaluated by the International Agency for Research on Cancer.Results: Three cohort studies and eight case-control studies were identified. There were inconsistent results regarding alcohol drinking and breast cancer risk among cohort studies. A significant positive association was observed in one, but another showed nonsignificant inverse association. Out of the eight case-control studies, two studies showed a significantly increased risk among women who drink daily and who had higher intake of alcohol, respectively. Experimental studies have supported the biological plausibility of a positive association between alcohol drinking and breast cancer risk.Conclusion: We conclude that epidemiologic evidence on the association between alcohol drinking and breast cancer risk remains insufficient in terms of both the number and methodological quality of studies among the Japanese population.