Autism severity and muscle strength: A correlation analysis
Autism severity and muscle strength: A correlation analysis
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DOI：
10.1016/j.rasd.2010.11.002
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发表时间：
2011-07-01
影响因子：
2.5
通讯作者：
Geier, Mark R.
中科院分区：
文献类型：
--
作者：
Kern, Janet K.;Geier, David A.;Geier, Mark R.
目前的研究调查了肌肉力量和儿童自闭症评定量表(CARS)衡量的自闭症严重程度之间的关系。对37名被诊断为自闭症谱系障碍(ASD)的儿童使用CARS进行评估，然后使用握力测力仪测试手部肌肉力量。然后进行统计分析，以检验自闭症严重程度与手部肌肉力量之间的关系。本研究中建立的模型表明，在调整了年龄、种族、性别、出生年份和既往的螯合治疗病史后，CARS评分是最大手部肌肉评分的显著预测因子。有证据表明，自闭症儿童的握力与疾病的严重程度有关。需要进一步的研究来确定肌肉无力的程度和一致性以及可能的治疗方法。(C)2010年由爱思唯尔有限公司出版。
The current study examined the relationship between muscle strength, as measured by hand grip strength, and autism severity, as measured by the Childhood Autism Rating Scale (CARS). Thirty-seven (37) children with a diagnosis of autism spectrum disorder (ASD) were evaluated using the CARS and then tested for hand muscle strength using a hand grip dynamometer. Statistical analysis was then conducted to examine the relationship between autism severity and hand muscle strength. The model generated in the present study showed that the CARS score is a significant predictor of Max Hand Muscle Score after adjustment for age, race, gender, year of birth, and a history of prior chelation therapy. Evidence suggests that hand grip strength in children with ASD is related to the severity of the disorder. Further research is needed to determine the extent and consistency of the muscle weakness and possible treatments. (C) 2010 Published by Elsevier Ltd.