Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery
Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery
复制标题
DOI：
10.1016/j.ophtha.2016.01.045
复制
发表时间：
2016-06-01
期刊：
影响因子：
13.7
通讯作者：
Rao, Rajesh C.
中科院分区：
文献类型：
--
作者：
Choudhry, Netan;Golding, John;Rao, Rajesh C.
目的：描述使用超宽视野（UWF）转向技术对视网膜周边成像的周边视网膜发现的光谱域光学相干断层扫描（SD OCT）特征。设计：观察性研究。参与者：共有68例患者（68只眼），具有19个周边视网膜特征。主要结果测量：基于光谱域OCT的结构特征。方法：19个周边视网膜特征，包括漩涡静脉、先天性视网膜色素上皮细胞肥大、睫状体平坦部、锯齿缘珍珠、典型囊样变性（TCD）、囊状视网膜丛、视网膜皱褶、格子状和鹅卵石样变性、视网膜裂孔、视网膜裂孔、孔源性视网膜脱离、通过外周临床检查确定了典型的退行性老年视网膜劈裂、外周激光凝固瘢痕、口齿、冷冻固定瘢痕（视网膜撕裂和治疗的视网膜母细胞瘤瘢痕）、骨针、无压力的白色和外周玻璃疣。这些实体的近红外扫描激光检眼镜图像和SD OCT被注册到UWF彩色photographs.Results：光谱域OCT解决所有周边发现的结构特征。在涡静脉中观察到脉络膜内扩张的低反射管状结构。在几个实体中观察到视网膜分层丢失、神经视网膜衰减、视网膜色素上皮丢失或肥大，包括先天性视网膜色素上皮肥大、锯齿缘珍珠、TCD、囊性视网膜簇、视网膜中央皱褶、格子状和鹅卵石变性。锯齿缘珍珠、锯齿缘齿、TCD、囊状视网膜簇、黄斑皱褶、视网膜裂孔及典型的退行性老年性视网膜劈裂症均可见视网膜内低反射间隙，提示囊状或裂液。玻璃体视网膜界面通常由靠近或附着于神经视网膜的致密皮质玻璃体的板层样结构组成，在大多数外周表现中清晰可见，证实了其与许多低风险和威胁视力的病理学相关，如格子状变性、视网膜皱褶、视网膜裂孔和孔源性视网膜脱离。视网膜周边的基于超宽视野转向的SD OCT成像对于当前市售的设备是可行的，并且提供了周边视网膜的详细解剖信息，包括先前未成像的良性和病理实体。这种成像技术可以加深我们对这些实体及其潜在相关的黄斑和全身病变的结构理解，并可能影响临床实践中的决策，特别是在具有远视网膜功能但难以获得视网膜专家的领域。(C)2016年美国眼科学会。
Purpose: To describe the spectral-domain optical coherence tomography (SD OCT) features of peripheral retinal findings using an ultra-widefield (UWF) steering technique to image the retinal periphery.Design: Observational study.Participants: A total of 68 patients (68 eyes) with 19 peripheral retinal features.Main Outcome Measures: Spectral-domain OCT-based structural features.Methods: Nineteen peripheral retinal features, including vortex vein, congenital hypertrophy of the retinal pigment epithelium, pars plana, ora serrata pearl, typical cystoid degeneration (TCD), cystic retinal tuft, meridional fold, lattice and cobblestone degeneration, retinal hole, retinal tear, rhegmatogenous retinal detachment, typical degenerative senile retinoschisis, peripheral laser coagulation scars, ora tooth, cryopexy scars (retinal tear and treated retinoblastoma scar), bone spicules, white without pressure, and peripheral drusen, were identified by peripheral clinical examination. Near-infrared scanning laser ophthalmoscopy images and SD OCT of these entities were registered to UWF color photographs.Results: Spectral-domain OCT resolved structural features of all peripheral findings. Dilated hyporeflective tubular structures within the choroid were observed in the vortex vein. Loss of retinal lamination, neural retinal attenuation, retinal pigment epithelium loss, or hypertrophy was seen in several entities, including congenital hypertrophy of the retinal pigment epithelium, ora serrata pearl, TCD, cystic retinal tuft, meridional fold, lattice, and cobblestone degenerations. Hyporeflective intraretinal spaces, indicating cystoid or schitic fluid, were seen in ora serrata pearl, ora tooth, TCD, cystic retinal tuft, meridional fold, retinal hole, and typical degenerative senile retinoschisis. The vitreoretinal interface, which often consisted of lamellae-like structures of the condensed cortical vitreous near or adherent to the neural retina, appeared clearly in most peripheral findings, confirming its association with many low-risk and vision-threatening pathologies, such as lattice degeneration, meridional folds, retinal breaks, and rhegmatogenous retinal detachments.Conclusions: Ultra-widefield steering-based SD OCT imaging of the retinal periphery is feasible with current commercially available devices and provides detailed anatomic information of the peripheral retina, including benign and pathologic entities, not previously imaged. This imaging technique may deepen our structural understanding of these entities and their potentially associated macular and systemic pathologies, and may influence decision-making in clinical practice, particularly in areas with teleretinal capabilities but poor access to retinal specialists. (C) 2016 by the American Academy of Ophthalmology.