Insights into the evolutionary process from patterns of DNA sequence variability

Insights into the evolutionary process from patterns of DNA sequence variability
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DOI:
10.1016/s0959-437x(97)80048-2
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发表时间:
1997-12-01
影响因子:
4
通讯作者:
Aquadro, CF
Aquadro, CF
中科院分区:
生物学2区
文献类型:
--
作者:
Aquadro, CF

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DNA序列多样性的研究,特别是在果蝇中,揭示了自然选择的复杂性,以及自然选择与基因组内和物种之间重组率变化的相互作用在确定不同基因和不同物种的序列变异性水平方面的重要性。适应性突变和有害突变的影响是显而易见的。将这些类型的研究扩展到其他生物体的工作已经认真开始。(C)Current Biology Ltd ISSN 0959-437X。
Studies of DNA sequence diversity, particularly in Drosophila, reveal both the complexity of natural selection and the importance of the interaction of natural selection and variation in rates of recombination within genomes and between species in determining levels of sequence variability in different genes and different species. The impact of both adaptive and deleterious mutations are evident. Extension of these types of studies to other organisms has begun in earnest. (C) Current Biology Ltd ISSN 0959-437X.