Functional connectivity among brain networks in continuous feedback of finger force
Functional connectivity among brain networks in continuous feedback of finger force
复制标题
DOI：
10.1016/j.neuroscience.2014.12.075
复制
发表时间：
2015-03
期刊：
影响因子：
3.3
通讯作者：
Han Zhang;Han Zhang;Y.-F. Zang;Y.-F. Zang
中科院分区：
文献类型：
--
作者：
Han Zhang;Han Zhang;Y.-F. Zang;Y.-F. Zang
运动反馈通常根据不同的反馈条件（如真实反馈和虚假反馈）参与不同的感觉和认知过程。人们认为这些过程可能依赖于大脑网络之间的功能连接。然而，尚不清楚两种反馈条件之间的网络连通性是否存在差异。为了解决这个问题，我们采用了一种新的模式，即手指力的连续反馈（8分钟），进行了功能磁共振成像（fMRI）研究。通过独立成分分析和功能连通性分析，我们发现与假反馈相比，真实反馈在执行网络（EN）和后验默认模式网络（pDMN）之间产生了更强的负连通性。更有趣的是，在真实反馈中，左额叶顶叶网络（lFPN）与pDMN表现出正连通性，而在虚假反馈中，lFPN与EN表现出连通性。这些结果表明，EN、pDMN和lFPN之间的连通性可能因真实和虚假反馈而不同，lFPN可能平衡pDMN和EN之间的竞争，从而支持运动反馈的感觉和认知过程。
Motor feedback usually engages distinct sensory and cognitive processes based on different feedback conditions, e.g., the real and sham feedbacks. It was thought that these processes may rely on the functional connectivity among the brain networks. However, it remains unclear whether there is a difference in the network connectivity between the two feedback conditions. To address this issue, we carried out a functional magnetic resonance imaging (fMRI) study by employing a new paradigm, i.e., continuous feedback (8 min) of finger force. Using independent component analysis and functional connectivity analysis, we found that as compared with the sham feedback, the real feedback recruited stronger negative connectivity between the executive network (EN) and the posterior default mode network (pDMN). More intriguingly, the left frontal parietal network (lFPN) exhibits positive connectivity with the pDMN in the real feedback while in the sham feedback, the lFPN shows connectivity with the EN. These results suggest that the connectivity among EN, pDMN, lFPN could differ depending on the real and sham feedbacks, and the lFPN may balance the competition between the pDMN and EN, thus supporting the sensory and cognitive processes of the motor feedback.