Detection of disease outbreaks by the use of oral manifestations.
Detection of disease outbreaks by the use of oral manifestations.
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通过口腔表现检测疾病爆发。
DOI：
10.1177/0022034508327546
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发表时间：
2009
影响因子：
7.6
通讯作者：
Schleyer,TKL
中科院分区：
文献类型：
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作者：
Torres-Urquidy,MH;Wallstrom,G;Schleyer,TKL
由生物恐怖分子引起的疾病的口腔表现可能是一种潜在的 生物监测的数据来源。这项研究的目的是确定 生物恐怖分子制剂引起的疾病的口腔表现， 急诊科报告中这些表现的患病率， 并基于它们评估检测算法。我们开发了一个软件 应用于检测自由文本中的口腔表现，并确定阳性 报告了三年的数据。报告的正常频率 与炭疽有关的临床表现（包括口腔溃疡-咽喉痛）占7.46%。 土拉菌血症发生率为6.91%。对于肉毒杆菌中毒和天花， 分别为0.55%和0.23%。我们模拟了这些生物恐怖主义疾病的爆发， 评估了我们系统的性能。检测算法在以下情况下表现更好： 天花和肉毒杆菌中毒而不是炭疽和兔热病。我们发现口腔 表现可以成为生物监测的宝贵工具。
Oral manifestations of diseases caused by bioterrorist agents could be a potential data source for biosurveillance. This study had the objectives of determining the oral manifestations of diseases caused by bioterrorist agents, measuring the prevalence of these manifestations in emergency department reports, and constructing and evaluating a detection algorithm based on them. We developed a software application to detect oral manifestations in free text and identified positive reports over three years of data. The normal frequency in reports for oral manifestations related to anthrax (including buccal ulcers-sore throat) was 7.46%. The frequency for tularemia was 6.91%. For botulism and smallpox, the frequencies were 0.55% and 0.23%. We simulated outbreaks for these bioterrorism diseases and evaluated the performance of our system. The detection algorithm performed better for smallpox and botulism than for anthrax and tularemia. We found that oral manifestations can be a valuable tool for biosurveillance.