Molecular variant analysis as an epidemiological tool to study persistence of cervical human papillomavirus infection.
Molecular variant analysis as an epidemiological tool to study persistence of cervical human papillomavirus infection.
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分子变异分析作为研究宫颈人乳头瘤病毒感染持续性的流行病学工具。
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
Antonio Ruiz
中科院分区：
文献类型：
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作者：
E. Franco;L. Villa;P. Rahal;Antonio Ruiz
Percy et al. (1) have reported that the detection rate (the proportion of hospital diagnoses of NPC in which the death certificate reflects the same diagnosis) and confirmation rate (the proportion of NPC deaths on death certificates that are also specified as NPC in hospital records) were poor. These rates for NPC (65.5% and 78.6%, respectively) are low compared with some other cancers, such as breast and lung cancers, where both rates are over 90% and indicate that, contrary to the implication by Lucas, relying upon death certificates to identify NPC may actually result in slightly fewer cases of NPC than from hospital-based diagnoses. This is because 34.5% of the NPC cases in hospital records are missed on death certificates, but only 21.4% of the death certificates that list NPC as the cause of death are inappropriately coded. The major error made by Lucas, however, is that she corrects only the death certificate diagnoses in the cohort and ignores the comparison population, which, in the NPC analysis of the National Cancer Institute's formaldehyde study (2), was the U.S. general population. The guiding principle in disease assessment in cohort studies is that diagnostic procedures applied to the cohort of interest must be the same as those applied to the referent population. The approach proposed by Lucas, i.e., removal of causes of death inaccurately classified as NPC in the cohort only, would actually bias the relative risk estimate downward because of the failure to correct for similar misclassification in the genera] U.S. population statistics. We agree that more accurate diagnosis of disease in cohort studies is desirable, but the suggestion of Lucas that investigators confirm all NPC cases in studies of formaldehyde is inappropriate, unless this procedure is applied to the comparison population as well.
HPV DNA 呈阳性的年轻女性的阴道镜和组织学检查结果以及人乳头瘤病毒 (HPV) DNA 检测变异性。
DOI：
10.1093/infdis/166.5.951
发表时间：
1992
期刊：
The Journal of infectious diseases
影响因子：
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作者：
Moscicki,AB;Palefsky,JM;Gonzales,J;Smith,G;Schoolnik,GK
通讯作者：
Schoolnik,GK
单链构象多态性分析检测人乳头瘤病毒16型非编码区序列变异。
DOI：
10.1093/infdis/168.3.610
发表时间：
1993
期刊：
The Journal of infectious diseases
影响因子：
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作者：
Xi,LF;Demers,W;Kiviat,NB;Kuypers,J;Beckmann,AM;Galloway,DA
通讯作者：
Galloway,DA