Studies on the structure and formation during spermatogenesis of the sulfoglycerogalactolipid of rat testis.
Studies on the structure and formation during spermatogenesis of the sulfoglycerogalactolipid of rat testis.
复制标题
大鼠睾丸磺基甘油半乳糖脂的结构和精子发生过程中的形成研究。
DOI：
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发表时间：
1974
期刊：
影响因子：
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通讯作者：
R. Murray...
中科院分区：
文献类型：
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作者：
M. Kornblatt;A. Knapp;M. Levine;H. Schachter;R. Murray...
对大鼠睾丸主要糖脂的结构研究证实了我们先前对该化合物的鉴定，即1- o -烷基-2- o -酰基-甘油-单半乳糖苷硫酸盐。酰基和烷基分别以棕榈酰基和棕榈酰基为主。在同一组织中发现的次要糖脂已被确定为这种糖脂的非硫酸盐形式。对未成熟大鼠、去垂体大鼠、正常小鼠和不育小鼠睾丸中硫甘半乳糖脂含量的检测表明，大部分化合物位于睾丸的生发细胞中，初级精母细胞是最早含有高水平脂质的生精细胞。半乳糖脂硫转移酶在大鼠睾丸原代精母细胞中也表现出最高的活性。
Structural studies on the major glycolipid of rat testis have confirmed our earlier identification of this compound as a 1-O-alkyl-2-O-acyl-glyceryl-monogalactoside sulfate. The acyl and alkyl groups are predominantly palmitoyl and palmityl groups, respectively. The minor glycolipid found in the same tissue has been identified as the non-sulfated form of this glycolipid. Examination of the levels of the sulfoglycerogalactolipid in the testes of immature rats, hypophysectomized rats, and normal and sterile mice indicates that the majority of the compound is located in the germinal cells of the testis and that the primary spermatocytes are the earliest spermatogenic cells to contain high levels of the lipid. Galactolipid sulfotransferase also shows peak activity in the primary spermatocytes of rat testis.