Palladium-catalyzed allylation of imines with allyl alcohols.
Palladium-catalyzed allylation of imines with allyl alcohols.
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DOI：
10.1002/chin.200527076
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发表时间：
2005-01
期刊：
影响因子：
5.2
通讯作者：
M. Shimizu;M. Kimura;Toshiya Watanabe;Y. Tamaru
中科院分区：
文献类型：
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作者：
M. Shimizu;M. Kimura;Toshiya Watanabe;Y. Tamaru
Pd（OAc）_2（10 mol %）-P（n-Bu）_3（20 mol %）-Et_3B（360 mol %）催化体系能促进烯丙醇与芳香醛和脂肪醛的茴香胺亚胺发生烯丙基化反应，并以较高的产率合成高烯丙基胺。该反应显示出独特的立体选择性，选择性地产生反异构体。[反应：见正文]
A catalytic system, Pd(OAc)2 (10 mol %)-P(n-Bu)3 (20 mol %)-Et3B (360 mol %), promotes allylic alcohols to undergo the allylation of anisidine-imines of aromatic and aliphatic aldehydes and furnishes homoallylamines in good to moderate yields. The reaction shows unique stereoselectivity, giving anti-isomers selectively. [reaction: see text]