The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.
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DOI：
10.1186/s40168-016-0168-z
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发表时间：
2016-06-03
期刊：
影响因子：
15.5
通讯作者：
MetaSUB International Consortium
中科院分区：
文献类型：
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作者：
MetaSUB International Consortium
地铁和城市生物群落的宏基因组学和元设计 (MetaSUB) 国际联盟是一项新颖的跨学科倡议，由基因组学、数据分析、工程、公共卫生和建筑等多个领域的专家组成。 MetaSUB 联盟的最终目标是通过城市环境中宏基因组的检测、测量和设计来提高城市利用率和规划。尽管对温度、气压、天气和人类活动（包括纵向）进行持续的测量，但跨领域的生态系统动态可以改变和改进城市的设计。 MetaSUB 联盟正在通过开发和测试宏基因组方法和标准来帮助这些工作，包括样本收集、DNA/RNA 分离、分类单元表征和数据可视化的优化方法。该联盟产生的数据可以为城市规划者、公共卫生官员和建筑设计师提供帮助。此外，该研究将继续导致新物种、抗菌素耐药性（AMR）标记全球图谱和新型生物合成基因簇（BGC）的发现。最后，我们注意到，工程宏基因组生态系统可以帮助实现反应更快、更安全和量化的城市。
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium is a novel, interdisciplinary initiative comprised of experts across many fields, including genomics, data analysis, engineering, public health, and architecture. The ultimate goal of the MetaSUB Consortium is to improve city utilization and planning through the detection, measurement, and design of metagenomics within urban environments. Although continual measures occur for temperature, air pressure, weather, and human activity, including longitudinal, cross-kingdom ecosystem dynamics can alter and improve the design of cities. The MetaSUB Consortium is aiding these efforts by developing and testing metagenomic methods and standards, including optimized methods for sample collection, DNA/RNA isolation, taxa characterization, and data visualization. The data produced by the consortium can aid city planners, public health officials, and architectural designers. In addition, the study will continue to lead to the discovery of new species, global maps of antimicrobial resistance (AMR) markers, and novel biosynthetic gene clusters (BGCs). Finally, we note that engineered metagenomic ecosystems can help enable more responsive, safer, and quantified cities.