LIGHT AND ELECTRON-MICROSCOPIC EXAMINATION OF THE MATURE DECIDUAL CELLS OF THE RAT WITH EMPHASIS ON THE ANTIMESOMETRIAL DECIDUA AND ITS DEGENERATION
LIGHT AND ELECTRON-MICROSCOPIC EXAMINATION OF THE MATURE DECIDUAL CELLS OF THE RAT WITH EMPHASIS ON THE ANTIMESOMETRIAL DECIDUA AND ITS DEGENERATION
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DOI：
10.1002/aja.1001720102
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发表时间：
1985-01-01
影响因子：
--
通讯作者：
ENDERS, AC
中科院分区：
文献类型：
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作者：
WELSH, AO;ENDERS, AC
在正常妊娠的第10-16天获得大鼠妊娠部位。光显微镜和EM检查的第10天网站揭示了一致的复杂模式的基质细胞形态。鉴定出6个不同的区域：上皮样蜕膜细胞的反子宫内膜区，形成含有胚胎和胚外膜的妊娠室;非胚性反子宫内膜蜕膜区，即蜕膜隐窝，其中细胞被大的细胞外间隙隔开;含有颗粒细胞和子宫内膜蜕膜细胞的子宫内膜区;一个棘状细胞区域，位于反子宫系膜蜕膜细胞的侧面，并与子宫系膜蜕膜细胞相连;和一个未分化的基质细胞区域，邻近子宫肌层。在第12天至第16天之间，反系膜蜕膜变得更薄，并最终脱落到新形成的子宫腔中。反子宫内膜蜕膜细胞的作用进行了讨论，参考滋养层细胞的侵袭，蛋白质合成，特别是重塑妊娠室。蜕膜和蜕膜瘤之间的差异被认为是。
Rat gestation sites were obtained on days 10-16 of normal pregnancy. Light microscopic and EM examination of day-10 sites revealed a consistent complex pattern of stromal cell morphologies. Six distinct regions were identified: an antimesometrial region of epithelioid decidual cells that form the gestation chamber containing the embryo and extraembryonic membranes; an abembryonic antimesometrial decidual region, the decidual crypt, where the cells are separated by large extracellular spaces; a mesometrial region with granule-containing cells and mesometrial decidual cells; a region of spiny cells that are lateral to the antimesometrial decidual cells and continuous with the mesometrial decidual cells; and a region of undifferentiated stromal cells adjacent to the myometrium. Between days 12 and 16, the antimesometrial decidua becomes thinner and is eventually sloughed into the newly formed uterine lumen. The role of the antimesometrial decidual cells is discussed with reference to trophoblast invasiveness, protein synthesis, and especially remodeling of the gestation chamber. Differences between decidua and deciduoma are considered.