Switching Between Intermolecular and Intramolecular Reactions Using Flow Microreactors. Lithiation of 2-Bromo-2'-Silylbiphenyls
Switching Between Intermolecular and Intramolecular Reactions Using Flow Microreactors. Lithiation of 2-Bromo-2'-Silylbiphenyls
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使用流动微反应器在分子间和分子内反应之间切换。
DOI：
10.1039/c6qo00257a
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
J.*
中科院分区：
文献类型：
--
作者：
Nagaki;A.*; Kim;S.; Miuchi;N.; Yamashita;H.; Hirose;K.; Yoshida;J.*
在流动微反应器中实现了2-锂-2 ′-硅基联苯的反应途径控制。通过选择合适的停留时间和温度区域，可以在亲电试剂的分子间反应和分子内反应之间进行有效的切换。
Reaction-pathway control of 2-lithio-2′-silylbiphenyls was accomplished in flow microreactor systems. Effective switching between the intermolecular reaction with an electrophile and the intramolecular reaction was performed at will by choosing an appropriate residence time and temperature region.