FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains

FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains
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DOI:
10.1016/s0092-8674(00)80256-1
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发表时间:
1997-05-30
期刊:
影响因子:
64.5
通讯作者:
Dean, C
Dean, C
中科院分区:
生物学1区
文献类型:
--
作者:
Macknight, R;Bancroft, I;Dean, C

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FCA编码拟南芥中向开花转变的强启动子。FCA已被克隆并显示编码含有两个RNA结合结构域和一个WW蛋白相互作用结构域的蛋白。这表明FCA在开花过程中参与转录本的转录后调节中发挥作用。FCA转录物选择性剪接,只有一种形式编码整个FCA蛋白。携带FCA基因融合强组成型35S启动子的植物开花较早,不同FCA转录本的比例和丰度发生了改变。因此,FCA似乎是一个组成部分的转录后级联参与控制开花时间。
A strong promoter of the transition to flowering in Arabidopsis is encoded by FCA. FCA has been cloned and shown to encode a protein containing two RNA-binding domains and a WW protein interaction domain. This suggests that FCA functions in the posttranscriptional regulation of transcripts involved in the flowering process. The FCA transcript is alternatively spliced with only one form encoding the entire FCA protein. Plants carrying the FCA gene fused to the strong constitutive 35S promoter flowered earlier, and the ratio and abundance of the different FCA transcripts were altered. Thus, FCA appears to be a component of a posttranscriptional cascade involved in the control of flowering time.