CELL INTERACTION BY MEANS OF SOLUBLE FACTORS (GAMONES) IN CONJUGATION OF BLEPHARISMA-INTERMEDIUM
CELL INTERACTION BY MEANS OF SOLUBLE FACTORS (GAMONES) IN CONJUGATION OF BLEPHARISMA-INTERMEDIUM
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DOI：
10.1016/0014-4827(73)90413-8
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发表时间：
1973-01-01
影响因子：
3.7
通讯作者：
BEYER, J
中科院分区：
文献类型：
--
作者：
MIYAKE, A;BEYER, J
B.中间体分化为互补交配型I和II。I型细胞分泌到培养基gamone I中，gamone I将II型细胞转化为配对形成细胞，同时诱导它们产生并分泌gamone II。这种配子将I型细胞转化为成对形成细胞。转化的细胞可以在所有三种可能的组合中结合，但只有异型对（I型-II型）经历接合特征的核变化。将Gamone I浓缩并部分纯化。该系统的适用性的细胞的调节机制的研究建议。
Cells ofB. intermediumdifferentiate into complementary mating types I and II. Type I cells excrete into the medium gamone I which transforms type II cells to pair-forming cells and at the same time induces them to produce and excrete gamone II. This gamone transforms type I cells to pair-forming cells. Transformed cells can unite in all three possible combinations but only heterotypic pairs (type I–type II) undergo nuclear changes characteristic of conjugation. Gamone I was concentrated and partially purified. The applicability of the system to the study of the regulation mechanism of the cell is suggested.