Anatomical basis of sun compass navigation II: The neuronal composition of the central complex of the monarch butterfly
Anatomical basis of sun compass navigation II: The neuronal composition of the central complex of the monarch butterfly
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DOI：
10.1002/cne.23214
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发表时间：
2013-02-01
影响因子：
2.5
通讯作者：
Reppert, Steven M.
中科院分区：
文献类型：
--
作者：
Heinze, Stanley;Florman, Jeremy;Reppert, Steven M.
每年秋天，北美东部的帝王蝶在它们的北方范围内进行长距离的迁徙，向南迁移到墨西哥的越冬地。迁移者使用时间补偿太阳罗盘来确定迁移过程中的方向。该指南针系统使用从太阳获得的天窗线索中提取的信息，这些信息根据一天中的时间进行补偿，并最终转换为适当的运动指令。中央复合体（CX）很可能是真正的太阳罗盘的位置，因为这个大脑区域的神经元被调谐到特定的天窗线索。为了帮助阐明太阳罗盘导航的神经基础，我们检查了CX及其相关脑区的神经元组成。我们生成了一个标准化版本的太阳罗盘neuropils，提供参考卷，以及一个共同的参考框架的神经元形态的注册。迁移和nonmigrating君主之间的体积比较证实了CX和相关的大脑区域在迁移行为的参与。通过登记超过55个神经元的34种细胞类型，我们能够描绘的主要输入通路的CX，输出通路，和内在神经元。将这些神经元素与其他物种，特别是沙漠蝗虫的神经元素进行比较，发现它们具有令人惊讶的保护程度。从这些物种间的数据，我们已经建立了一个保守的核心网络的CX的关键组成部分，可能由物种特异性神经元，这可能共同构成的CX执行的计算的神经基板的补充。J.Comp.神经元521：267298，2013. (c)2012 Wiley Periodicals，Inc.
Each fall, eastern North American monarch butterflies in their northern range undergo a long-distance migration south to their overwintering grounds in Mexico. Migrants use a time-compensated sun compass to determine directionality during the migration. This compass system uses information extracted from sun-derived skylight cues that is compensated for time of day and ultimately transformed into the appropriate motor commands. The central complex (CX) is likely the site of the actual sun compass, because neurons in this brain region are tuned to specific skylight cues. To help illuminate the neural basis of sun compass navigation, we examined the neuronal composition of the CX and its associated brain regions. We generated a standardized version of the sun compass neuropils, providing reference volumes, as well as a common frame of reference for the registration of neuron morphologies. Volumetric comparisons between migratory and nonmigratory monarchs substantiated the proposed involvement of the CX and related brain areas in migratory behavior. Through registration of more than 55 neurons of 34 cell types, we were able to delineate the major input pathways to the CX, output pathways, and intrinsic neurons. Comparison of these neural elements with those of other species, especially the desert locust, revealed a surprising degree of conservation. From these interspecies data, we have established key components of a conserved core network of the CX, likely complemented by species-specific neurons, which together may comprise the neural substrates underlying the computations performed by the CX. J. Comp. Neurol. 521:267298, 2013. (c) 2012 Wiley Periodicals, Inc.