Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar
Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar
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DOI：
10.1093/bioinformatics/btq028
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发表时间：
2010-03-15
期刊：
影响因子：
5.8
通讯作者：
Yip, Yum L.
中科院分区：
文献类型：
--
作者：
Mottaz, Anais;David, Fabrice P. A.;Yip, Yum L.
SwissVar门户网站通过独特的搜索引擎提供对UniProtKB/Swiss-Prot数据库中单个氨基酸多态性和疾病的全面收集的访问。特别是，它可以直接访问新改进的Swiss-Prot变体页面。该门户网站的主要优势在于，它提供了查询类似疾病的可能性，以及潜在的蛋白质产品和每个变体的分子细节。在最近提出的疾病分子观点的背景下，SwissVar门户网站应该处于一个独特的位置，为研究人员提供有价值的信息，并推动这一领域的研究。
The SwissVar portal provides access to a comprehensive collection of single amino acid polymorphisms and diseases in the UniProtKB/Swiss-Prot database via a unique search engine. In particular, it gives direct access to the newly improved Swiss-Prot variant pages. The key strength of this portal is that it provides a possibility to query for similar diseases, as well as the underlying protein products and the molecular details of each variant. In the context of the recently proposed molecular view on diseases, the SwissVar portal should be in a unique position to provide valuable information for researchers and to advance research in this area.