A hitchhiker's guide to lesion-behaviour mapping
A hitchhiker's guide to lesion-behaviour mapping
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DOI：
10.1016/j.neuropsychologia.2017.10.021
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发表时间：
2018-07-01
期刊：
影响因子：
2.6
通讯作者：
Karnath, Hans-Otto
中科院分区：
文献类型：
--
作者：
de Haan, Bianca;Karnath, Hans-Otto
病变行为映射是一种有影响力和流行的方法来解剖定位人类大脑的认知功能。从患者选择、病变位置和患者行为评估、空间归一化、统计检验到获得结果的解剖解释等多种考虑因素，都是优化病变行为映射研究并得出有意义结论所必需的。在这里，我们提供了一个搭便车的指南，为典型的病变行为映射研究管道的每一步提供实用的指导和参考。
Lesion-behaviour mapping is an influential and popular approach to anatomically localise cognitive brain functions in the human brain. Multiple considerations, ranging from patient selection, assessment of lesion location and patient behaviour, spatial normalisation, statistical testing, to the anatomical interpretation of obtained results, are necessary to optimize a lesion-behaviour mapping study and arrive at meaningful conclusions. Here, we provide a hitchhiker's guide, giving practical guidelines and references for each step of the typical lesion-behaviour mapping study pipeline.