In vivo hyperpolarized 129Xe NMR spectroscopy in tumors

In vivo hyperpolarized 129Xe NMR spectroscopy in tumors
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肿瘤体内超极化 129Xe NMR 波谱

DOI:
--
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发表时间:
2001
影响因子:
3.3
通讯作者:
A. Bifone
A. Bifone
中科院分区:
医学3区
文献类型:
--
作者:
J. Wolber;D. McIntyre;L. Rodrigues;P. Carnochan;J. Griffiths;M. Leach;A. Bifone

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首次在实验性肿瘤中进行了体内超极化129 NMR研究。将超极化的129 μ M溶解在溶液中,并在大鼠的GH-3泌乳素瘤和小鼠的RIF-1纤维肉瘤中瘤内注射。两种肿瘤类型的129 NMR谱和表观自旋晶格弛豫时间存在特征性差异。这些差异进行了讨论的载体介质和组织隔间之间的氙交换。Magn Reson Med 46:586-591,2001.© 2001 Wiley利斯公司
The first in vivo hyperpolarized 129Xe NMR study in experimental tumors is presented. Hyperpolarized 129Xe was dissolved in solutions, and was injected intratumorally in GH‐3 prolactinomas in rats and RIF‐1 fibrosarcomas in mice. The 129Xe NMR spectra and apparent spin‐lattice relaxation times in the two tumor types present characteristic differences. These differences are discussed in terms of xenon exchange between the carrier medium and the tissue compartments. Magn Reson Med 46:586–591, 2001. © 2001 Wiley‐Liss, Inc.
地塞米松对 RIF-1 肿瘤血管功能的影响。
DOI: --
发表时间: 1986
期刊: Cancer research
影响因子: 11.2
作者:
Braunschweiger,PG;Schiffer,LM
通讯作者: Schiffer,LM