Synchrotron Radiation, in Biology and Medicine
Synchrotron Radiation, in Biology and Medicine
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DOI：
10.12693/aphyspola.114.309
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发表时间：
2008-08
影响因子：
0.7
通讯作者：
J. Pelka
中科院分区：
文献类型：
--
作者：
J. Pelka
本文简要介绍了同步辐射的性质、生物医学研究的重要性以及使用同步辐射源的基本方法。特别注意的是辐射损伤，这迫使修改的技术和程序的同步辐射研究在生物学相对于材料科学的方法。本文简要介绍了自由电子激光器的成像、结构和超快动力学研究等新的基础技术的原理和迅猛发展。一个特别的部分是专门用于检测病原体，包括病毒，作为同步加速器技术的一个可能的应用太赫兹辐射的最新研究。最近实现的病毒检测灵敏度和选择性与经典的生物分析方法相当。本文旨在为各科学技术学科的研究人员，谁有兴趣在生物和医学问题的同步辐射应用合作，并提供了一套相关的参考。
The properties of synchrotron radiation, substantial for biomedical research, as well as basic methods using these sources are briefly discussed. Particular attention is paid to radiation damage, which imposes the modification of techniques and procedures for synchrotron research in biology relative to the approach in materials science. The principles and the stormy development of new basic techniques such as imaging, structural and ultrafast dynamics studies developed for free-electron lasers are briefly reported. A special section is dedicated to the latest research with terahertz radiation on detection of pathogens, including viruses, as a possible application of synchrotron technology. Recently achieved viral detection sensitivity and selectivity are comparable to classical bioanalytical methods. This review is intended to researchers of various science and technology disciplines with, who are interested to cooperate in application of synchrotron radiation for issues of biology and medicine and provides a set of relevant references.