Outcomes of dialysis patients with critical limb ischemia after revascularization compared with patients with normal renal function
Outcomes of dialysis patients with critical limb ischemia after revascularization compared with patients with normal renal function
复制标题
DOI：
10.1016/j.jvs.2017.12.048
复制
发表时间：
2018-09-01
影响因子：
4.3
通讯作者：
Lang, Werner
中科院分区：
文献类型：
--
作者：
Meyer, Alexander;Fiessler, Cornelia;Lang, Werner
目的：分析终末期肾病（ESRD）伴重度肢体缺血患者与正常肾功能（非ESRD）患者下肢血运重建术后的中期结局及可能的影响因素。方法：通过查询德国多中心“危重肢体缺血患者一线治疗”注册中心（CRITISCH）进行数据收集；纳入102例ESRD患者和674例非ESRD患者。分析了四种不同的治疗方式：搭桥手术、血管内治疗（EVT）、股动脉内膜切除术和无血管干预（保守治疗或原发性大截肢）。预定义的终点是无截肢生存（AFS）、死亡、主要截肢和再干预。建立Cox回归模型分析结局参数的独立危险因素。结果：ESRD患者2年时AFS发生率较低(ESRD为35.4%，非ESRD为67.2%
Objective: An analysis was conducted of intermediate outcomes and possible influencing factors in patients with end-stage renal disease (ESRD) and critical limb ischemia after lower limb revascularization compared with patients with regular renal function (non-ESRD).Methods: Data collection was performed by inquiry of the German multicenter registry of First-Line Treatments in Patients with Critical Limb Ischemia (CRITISCH); 102 ESRD patients and 674 non-ESRD patients were included. Four different therapy modalities were analysed: bypass surgery, endovascular therapy (EVT), femoral artery endarterectomy, and no vascular intervention (conservative treatment or primary major amputation). Predefined end points were amputation-free survival (AFS), death, major amputation, and reintervention. Cox regression models were built to analyze independent risk factors for outcome parameters.Results: ESRD patients showed inferior results at 2 years in the rate of AFS (ESRD, 35.4%; non-ESRD, 67.2%; P