Rapid Staphylococcus aureus agr type determination by a novel multiplex real-time quantitative PCR assay

Rapid Staphylococcus aureus agr type determination by a novel multiplex real-time quantitative PCR assay
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DOI:
10.1128/jcm.44.5.1892-1895.2006
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发表时间:
2006-05-01
影响因子:
9.4
通讯作者:
Schrenzel, J
Schrenzel, J
中科院分区:
医学2区
文献类型:
--
作者:
Francois, P;Koessler, T;Schrenzel, J

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辅助基因调节子(accessory gene regulator,agr)是金黄色葡萄球菌中参与控制细菌毒力因子表达的重要调控成分。建立了一种快速检测沙门氏菌的多重实时荧光定量PCR方法。aureus agr型。这种检测方法是一种快速和负担得起的替代基于序列的战略,用于评估相关的流行病学信息。
The accessory gene regulator (agr) is a crucial regulatory component of Staphylococcus aureus involved in the control of bacterial virulence factor expression. We developed a real-time multiplex quantitative PCR assay for the rapid determination of S. aureus agr type. This assay represents a rapid and affordable alternative to sequence-based strategies for assessing relevant epidemiological information.