Face-Identity Change Activation Outside the Face System: "Release from Adaptation" May Not Always Indicate Neuronal Selectivity
Face-Identity Change Activation Outside the Face System: "Release from Adaptation" May Not Always Indicate Neuronal Selectivity
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DOI：
10.1093/cercor/bhp272
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发表时间：
2010-09-01
期刊：
影响因子：
3.7
通讯作者：
Kriegeskorte, Nikolaus
中科院分区：
文献类型：
--
作者：
Mur, Marieke;Ruff, Douglas A.;Kriegeskorte, Nikolaus
人脸识别是一个复杂的认知过程，需要不同的神经元表征个体的面孔。以前的功能性磁共振成像（fMRI）研究使用的“fMRI适应”技术表明，在面孔选择性区域，包括梭状面孔区（FFA）的存在的面孔身份表征。在这里，我们提出的面孔身份适应的研究结果，没有很好地解释在面孔身份表征。我们进行了血氧水平依赖（BOLD）fMRI测量，而参与者在整个实验中反复看到熟悉的面孔。我们发现面部选择性区域中重复面部的激活减少，正如先前研究所预期的那样。然而，我们在非面部选择性区域发现了类似的效应，包括海马旁位置区（PPA）和早期视觉皮层（EVC）。这些影响存在于精确图像（相同视图和照明）以及不同图像（不同视图和/或照明）重复中，但对于精确图像重复更普遍。鉴于PPA和EVC的已知功能特性，它们似乎不太可能包含特定于域的面部身份表征。其他解释包括一般注意力效应和连接区域激活的遗留。这些结果提醒我们，功能磁共振成像刺激变化效应可能有一系列的原因，并没有提供确凿的证据，神经元表示的变化刺激属性。
Face recognition is a complex cognitive process that requires distinguishable neuronal representations of individual faces. Previous functional magnetic resonance imaging (fMRI) studies using the "fMRI-adaptation" technique have suggested the existence of face-identity representations in face-selective regions, including the fusiform face area (FFA). Here, we present face-identity adaptation findings that are not well explained in terms of face-identity representations. We performed blood-oxygen level-dependent (BOLD) fMRI measurements, while participants viewed familiar faces that were shown repeatedly throughout the experiment. We found decreased activation for repeated faces in face-selective regions, as expected based on previous studies. However, we found similar effects in regions that are not face-selective, including the parahippocampal place area (PPA) and early visual cortex (EVC). These effects were present for exact-image (same view and lighting) as well as different-image (different view and/or lighting) repetition, but more widespread for exact-image repetition. Given the known functional properties of PPA and EVC, it appears unlikely that they contain domain-specific face-identity representations. Alternative interpretations include general attentional effects and carryover of activation from connected regions. These results remind us that fMRI stimulus-change effects can have a range of causes and do not provide conclusive evidence for a neuronal representation of the changed stimulus property.