Unique strategy for the assembly of the carbon skeleton of guanacastepene a using an allenic Pauson-Khand-type reaction
Unique strategy for the assembly of the carbon skeleton of guanacastepene a using an allenic Pauson-Khand-type reaction
复制标题
DOI：
10.1021/ol035322x
复制
发表时间：
2003-09-18
期刊：
影响因子：
5.2
通讯作者：
Gao, D
中科院分区：
文献类型：
--
作者：
Brummond, KM;Gao, D
[图表]已经使用铑（I）催化的丙二烯Pauson-Khand反应开发了一种获得guanacastepene A的高度官能化的三环核心的方法。这种方法构成了用于合成这种三环框架的概念上新颖的策略，由此首先形成六元环，然后同时形成五元环和七元环。
[GRAPHICS]An approach to the highly functionalized tricyclic core of guanacastepene A has been developed using a rhodium(I)-catalyzed allenic Pauson-Khand reaction, This approach constitutes a conceptually novel strategy for the synthesis of this tricyclic framework, whereby the six-membered ring is formed intially followed by simultaneous formation of the five- and seven-membered rings.