Stroke patients' evolving symptoms assessed by tractography
Stroke patients' evolving symptoms assessed by tractography
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DOI：
10.1002/jmri.20215
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发表时间：
2004-12-01
影响因子：
4.4
通讯作者：
Nishimura, T
中科院分区：
文献类型：
--
作者：
Yamada, K;Ito, H;Nishimura, T
目的：为了检验这一假设，间隔演变的位置所描绘的感觉运动道相对于梗死（“道梗死关系”）可能与中风受害者的症状progress.Materials和方法：患者（N = 7）谁经历了多次扩散张量成像（DTI）的研究，在症状进展被列入本研究。使用单次激发回波平面成像（EPI）技术进行DTI，在6个方向上使用运动探测梯度，b值为800秒/mm（2），6个图像平均值。总扫描时间为4分24秒。纤维跟踪的感觉运动通路进行，这些道的位置进行了回顾性评估，在有关的演变symptoms.Results：5的7例患者表现出间隔扩大的梗死扩散加权（DW）图像。在这些病例中，有2例病变扩大到涉及感觉运动束，而在3例病例中，病变扩大到接近感觉运动束。在剩下的两种情况下，没有间隔扩大的梗死，因此，牵引梗死的关系不能占这些cases.Conclusion的症状的演变：一个牵引梗死的关系可以观察到与使用的纤维跟踪技术，和结果可能会提高我们的理解中风患者的症状进展。(C)2004 Wiley-Liss，Inc.
Purpose: To test the hypothesis that an interval evolution in the location of the depicted sensorimotor tract relative to the infarct (the "tract-infarct relationship") may be related to stroke victims' symptom progression.Materials and Methods: Patients (N = 7) who underwent multiple diffusion-tensor imaging (DTI) studies during symptomatic progression were included in this study. DTI was performed using a single-shot echo-planar imaging (EPI) technique with a motion-probing gradient in six orientations, a b-value of 800 seconds/mm(2), and six image averages. The total scan time was four minutes and 24 seconds. Fiber-tracking of the sensorimotor pathways was performed, and the locations of these tracts were retrospectively assessed in relation to the evolution of the symptoms.Results: Five of the seven patients showed an interval enlargement of the infarct on diffusion-weighted (DW) images. In two of these cases the lesion enlarged to involve the sensorimotor tracts, while in three cases the lesion enlarged only so far to come into close proximity to the sensorimotor tract. In the remaining two cases there was no interval enlargement of the infarct, and therefore the tract-infarct relationship could not account for the evolution of the symptoms in these cases.Conclusion: A tract-infarct relationship can be observed with the use of a fiber-tracking technique, and the results may improve our understanding of the symptom progression seen in stroke victims. (C) 2004 Wiley-Liss, Inc.