Injury severity variables as predictors of WeeFIM scores in pediatric TBI: Time to follow commands is best

Injury severity variables as predictors of WeeFIM scores in pediatric TBI: Time to follow commands is best
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DOI:
10.3233/prm-2009-0092
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发表时间:
2009-01-01
影响因子:
1.9
通讯作者:
Salorio, Cynthia F.
Salorio, Cynthia F.
中科院分区:
其他
文献类型:
--
作者:
Suskauer, Stacy J.;Slomine, Beth S.;Salorio, Cynthia F.

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小儿创伤性脑损伤(TBI)后,预期功能的早期预后对于优化护理非常重要。研究了几种常见的脑损伤严重程度指标预测TBI儿童功能结局的能力;研究的严重程度变量为格拉斯哥昏迷量表(GCS)评分、遵守命令时间(TFC)、创伤后遗忘持续时间(PTA)和意识受损总持续时间(TFC+PTA)。在出院时使用儿童功能独立性测量(Weewealth)对住院康复(n = 120)和出院后3个月的儿童亚组进行结局评估。使用GCS、TFC、PTA和TFC+PTA进行相关性和多元线性回归分析,以预测年龄校正后的Weekly评分。将TFC和PTA持续时间作为单独变量和组合变量(TFC+PTA)输入的模型均能显著预测出院时的Weekly评分;然而,TFC占Weekly评分方差的最大部分。在接受住院康复治疗的中重度TBI儿童中,TFC是出院和随访时一般功能结局的最佳预测因素。我们的研究结果强调需要仔细和一致的评估TFC,以帮助预测功能的结果,尽早和准确。
After pediatric traumatic brain injury (TBI), early prognosis of expected function is important for optimizing care. The power of several common brain injury severity measures for predicting functional outcome in children with TBI was investigated; the severity variables studied were Glasgow Coma Scale (GCS) score, time to follow commands (TFC), duration of post-traumatic amnesia (PTA), and total duration of impaired consciousness (TFC+PTA). Outcome was assessed using the Functional Independence Measure for Children (WeeFIM) at discharge from inpatient rehabilitation (n = 120) and, in a subset of children, at 3 months following discharge. Correlations and multiple linear regression analyses were conducted using GCS, TFC, PTA, and TFC+PTA to predict age-corrected WeeFIM scores. Models in which TFC and PTA duration were entered as separate variables and as a combined variable (TFC+PTA) were all significantly predictive of WeeFIM scores at discharge; however, TFC accounted for the greatest portion of variance in WeeFIM scores. Among children with moderate to severe TBI who received inpatient rehabilitation, TFC was the best predictor of general functional outcome at discharge and follow-up. Our findings highlight the need for careful and consistent assessment of TFC to assist in predicting functional outcomes as early and accurately as possible.