POSTOPERATIVE ANALGESICS FOR CHILDREN AND ADOLESCENTS - PRESCRIPTION AND ADMINISTRATION
POSTOPERATIVE ANALGESICS FOR CHILDREN AND ADOLESCENTS - PRESCRIPTION AND ADMINISTRATION
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DOI：
10.1016/0885-3924(94)90161-9
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发表时间：
1994-02-01
影响因子：
4.7
通讯作者：
SAVEDRA, MC
中科院分区：
文献类型：
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作者：
TESLER, MD;WILKIE, D;SAVEDRA, MC
在131名8-17岁的儿童和青少年中，在手术后5天测量疼痛并检查镇痛治疗。将镇痛数据转换为10 mg肌内吗啡等效剂量（IMMSEQ），并指定其适合或不适合体重。计算与给药途径相关的镇痛起效、峰值和持续时间，并进行疼痛评估。儿童报告在许多身体部位出现中度疼痛。最初，除两名儿童外，所有儿童都接受了处方，最终除一名儿童外，所有儿童都接受了止痛药。处方和给药剂量经常低于体重推荐剂量。当评估疼痛时，三分之二的儿童超出了止痛作用。在术后5天的每一天，IMMSEQ剂量与疼痛强度评分之间均观察到弱至中等强度的相关性。不幸的是，研究结果表明，儿童在经历术后疼痛时继续治疗不足。
Pain was measured and analgesic treatment examined in 131 children and adolescents 8-17 years of age, for 5 days after surgery. Analgesic data were converted to 10 mg intramuscular morphine-equivalent doses (IMMSEQ) and were designated appropriate or inappropriate for body weight. Analgesic onset, peak, and duration were calculated in relation to administration routes and the time pain assessments were made. Children reported moderately severe pain in many body locations. Initially, all but two children were prescribed and ultimately all but one received analgesics. Prescribed and administered doses were frequently less than doses recommended for weight. Two-thirds of the children were beyond analgesic action when pain was assessed. Weak to moderately strong associations were noted between IMMSEQ doses and pain intensity scores on each of the 5 postoperative days. Unfortunately, findings indicate that children continue to be undertreated when they experience postoperative pain.