Biogenesis of mammalian microRNAs: a global view.

Biogenesis of mammalian microRNAs: a global view.
复制标题

DOI:
10.1016/j.gpb.2012.06.004
复制
发表时间:
2012-10
影响因子:
9.5
通讯作者:
Zeng, Yan
Zeng, Yan
中科院分区:
生物学2区
文献类型:
--
作者:
Graves, Paul;Zeng, Yan

文献摘要

参考文献

被引文献

相似文献

微小RNA(microRNAs,miRNAs)是一类长度约为22个核苷酸的非编码RNA,是真核生物基因表达的重要调控因子。miRNA首先转录为长的初级转录物,然后经过一系列加工步骤产生单链成熟miRNA。本文综述了我们目前对哺乳动物miRNA表达的机制和调控的认识,并指出了可能增强我们对体内miRNA生产的特异性和效率如何控制的理解的研究领域。
MicroRNAs (miRNAs) are approximately 22-nucleotide-long non-coding RNAs that are important regulators of gene expression in eukaryotes. miRNAs are first transcribed as long primary transcripts, which then undergo a series of processing steps to produce the single-stranded mature miRNAs. This article reviews our current knowledge of the mechanism and regulation of mammalian miRNA expression and points out areas of research that may enhance our understanding of how the specificity and efficiency of miRNA production is controlled in vivo.
DOI: 10.1016/j.bbagrm.2011.05.015
发表时间: 2011-11
影响因子: 4.7
作者:
Feng, Yong;Zhang, Xiaoxiao;Song, Qingfeng;Li, Tongbin;Zeng, Yan
通讯作者: Zeng, Yan
DOI: 10.1016/j.molcel.2009.12.016
发表时间: 2010-01-15
期刊: Molecular cell
影响因子: 16
作者:
Bogerd HP;Karnowski HW;Cai X;Shin J;Pohlers M;Cullen BR
通讯作者: Cullen BR
DOI: 10.1038/nature03868
发表时间: 2005-08-04
期刊: NATURE
影响因子: 64.8
作者:
Chendrimada, TP;Gregory, RI;Shiekhattar, R
通讯作者: Shiekhattar, R
DOI: 10.1101/gad.1705308
发表时间: 2008-10-15
影响因子: 10.5
作者:
Babiarz, Joshua E.;Ruby, J. Graham;Blelloch, Robert
通讯作者: Blelloch, Robert
DOI: 10.1126/science.1190809
发表时间: 2010-06-25
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Cifuentes D;Xue H;Taylor DW;Patnode H;Mishima Y;Cheloufi S;Ma E;Mane S;Hannon GJ;Lawson ND;Wolfe SA;Giraldez AJ
通讯作者: Giraldez AJ