Recent advances in imaging and understanding interstitial cystitis.
Recent advances in imaging and understanding interstitial cystitis.
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DOI：
10.12688/f1000research.16096.1
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发表时间：
2018-01-01
期刊：
影响因子：
--
通讯作者：
Chermansky, Christopher
中科院分区：
文献类型：
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作者：
Tyagi, Pradeep;Moon, Chan-Hong;Chermansky, Christopher
间质性膀胱炎/膀胱痛综合征(IC/BPS)是一种与剧烈的盆腔疼痛和膀胱储存症状相关的衰弱症状。由于诊断困难，患病率估计因使用的方法不同而不同。目前也缺乏已被证实的成像工具和生物标记物来帮助IC/BPS与其他泌尿系疾病(膀胱过度活动、外阴疼痛、子宫内膜异位症和前列腺炎)的鉴别。目前关于IC/BPS病因和病理的不确定性最终影响其及时和成功的治疗，并阻碍未来的药物开发。这篇综述将包括磁共振成像等成像方法的最新进展，这些方法可以促进对IC/BPS的理解，并指导药物开发。
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating condition associated with intense pelvic pain and bladder storage symptoms. Since diagnosis is difficult, prevalence estimates vary with the methodology used. There is also a lack of proven imaging tools and biomarkers to assist in differentiation of IC/BPS from other urinary disorders (overactive bladder, vulvodynia, endometriosis, and prostatitis). Current uncertainty regarding the etiology and pathology of IC/BPS ultimately impacts its timely and successful treatment, as well as hampers future drug development. This review will cover recent developments in imaging methods, such as magnetic resonance imaging, that advance the understanding of IC/BPS and guide drug development.