Plaque At RISK (PARISK): prospective multicenter study to improve diagnosis of high-risk carotid plaques
Plaque At RISK (PARISK): prospective multicenter study to improve diagnosis of high-risk carotid plaques
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DOI：
10.1111/ijs.12167
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发表时间：
2014-08-01
影响因子：
6.7
通讯作者：
van der Lugt, A.
中科院分区：
文献类型：
--
作者：
Truijman, M. T. B.;Kooi, M. E.;van der Lugt, A.
背景有症状性颈动脉狭窄的患者再发卒中的风险很高。到目前为止，对最近发生脑血管事件的患者进行颈动脉内膜切除术的决定主要是基于同侧颈动脉的狭窄程度。然而，额外的动脉粥样硬化斑块特征可能是更好的中风预测因子，从而允许更精确地选择颈动脉内膜切除术的患者。目的和假说我们调查了这样的假设，即单独或联合使用磁共振成像、多层螺旋CT血管成像、超声和经颅多普勒对颈动脉斑块特征的评估可以改善对一组患者的识别
Background Patients with symptomatic carotid artery stenosis are at high risk for recurrent stroke. To date, the decision to perform carotid endarterectomy in patients with a recent cerebrovascular event is mainly based on degree of stenosis of the ipsilateral carotid artery. However, additional atherosclerotic plaque characteristics might be better predictors of stroke, allowing for more precise selection of patients for carotid endarterectomy.Aims and hypothesis We investigate the hypothesis that the assessment of carotid plaque characteristics with magnetic resonance imaging, multidetector-row computed tomography angiography, ultrasonography, and transcranial Doppler, either alone or in combination, may improve identification of a subgroup of patients with