Exercise testing and training in people with Huntington's disease
Exercise testing and training in people with Huntington's disease
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DOI：
10.1177/0269215514540921
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发表时间：
2015-02-01
影响因子：
3
通讯作者：
Busse, M.
中科院分区：
文献类型：
--
作者：
Dawes, H.;Collett, J.;Busse, M.
目的：探讨运动对亨廷顿病（HD）患者的影响。设计：干预研究前后随机分组的实验观察研究。设置：社区。受试者：HD患者（n=30）和健康对照组（n=20）。HD组13人被随机分配到一个运动训练计划中，主要测量：在次极量踏车运动试验（3分钟无负荷和9分钟65%-75%HR最大阶段）中的心率（HR）和Borg-CR 10量表（RPE）上的自感知消耗。对8名HD患者进行了12周的健身房和家庭步行锻炼。结果：HD患者在9分钟时的工作率较低（8242（0-195）vs 107 +/- 35（50 - 185）W（P
Objective: To explore exercise response in people with Huntington's disease (HD).Design: Experimental observational study with a randomly allocated subgroup before/after interventional study.Setting: Community.Subjects: People with HD (n=30) and a healthy comparator group (n=20). Thirteen people from the HD group were randomly allocated to an exercise training program.Main measures: Heart rate (HR) and perceived exertion on the Borg-CR10 scale (RPE) during a submaximal cycle ergometer exercise test (three minute unloaded and nine minute 65%-75%HRmaximum phase). Expired air and lactate measures were available for 8 people with HD during the exercise.Intervention: A 12 week gym and home walking exercise programme (n=13).Results: People with HD achieved a lower work rate at nine minutes (8242(0-195) v 107 +/- 35(50 -185) Watts (p