Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline
Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline
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DOI：
10.1210/jc.2011-2803
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发表时间：
2012-08-01
影响因子：
5.8
通讯作者：
Sullivan, Scott
中科院分区：
文献类型：
--
作者：
De Groot, Leslie;Abalovich, Marcos;Sullivan, Scott
目的：其目的是更新2007年发布的妊娠期和产后甲状腺功能障碍管理指南。2007年版和2012年版之间的变化总结见补充数据（发表在内分泌学会期刊在线网站http://jcem.endojournals.org上）。证据：本循证指南是根据美国预防服务工作组制定的，将项目分级为A、B、C、D或I级，根据证据的强度和净效益的大小（利益减去危害）以及建议、评估、发展、共识过程：指南是通过一系列电子邮件、电话会议和一次面对面会议制定的。工作队在一位医学作家的帮助下编写了初稿，并由内分泌学会、亚洲和大洋洲甲状腺协会以及拉丁美洲甲状腺协会的成员进行了审查和评论。内分泌学会理事会审查并批准了第二稿。在每个阶段的审查，特别工作组收到书面意见，并纳入实质性的changes.Conclusions：实践指南的诊断和治疗甲状腺相关的医疗问题的患者之前，怀孕期间和产后间隔。这些包括循证方法来评估疾病的原因，治疗它，并管理甲状腺功能减退症，甲状腺功能亢进症，妊娠期甲状腺功能亢进症，甲状腺自身免疫，甲状腺肿瘤，碘营养，产后甲状腺炎和甲状腺疾病筛查。还介绍了治疗中使用的治疗剂的适应症和副作用。（临床内分泌代谢杂志97：2543-2565，2012）
Objective: The aim was to update the guidelines for the management of thyroid dysfunction during pregnancy and postpartum published previously in 2007. A summary of changes between the 2007 and 2012 version is identified in the Supplemental Data (published on The Endocrine Society's Journals Online web site at http://jcem.endojournals.org).Evidence: This evidence-based guideline was developed according to the U.S. Preventive Service Task Force, grading items level A, B, C, D, or I, on the basis of the strength of evidence and magnitude of net benefit (benefits minus harms) as well as the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence.Consensus Process: The guideline was developed through a series of e-mails, conference calls, and one face-to-face meeting. An initial draft was prepared by the Task Force, with the help of a medical writer, and reviewed and commented on by members of The Endocrine Society, Asia and Oceania Thyroid Association, and the Latin American Thyroid Society. A second draft was reviewed and approved by The Endocrine Society Council. At each stage of review, the Task Force received written comments and incorporated substantive changes.Conclusions: Practice guidelines are presented for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval. These include evidence-based approaches to assessing the cause of the condition, treating it, and managing hypothyroidism, hyperthyroidism, gestational hyperthyroidism, thyroid autoimmunity, thyroid tumors, iodine nutrition, postpartum thyroiditis, and screening for thyroid disease. Indications and side effects of therapeutic agents used in treatment are also presented. (J Clin Endocrinol Metab 97: 2543-2565, 2012)