Treatment of small colorectal polyps: a population-based study of the risk of subsequent carcinoma.
Treatment of small colorectal polyps: a population-based study of the risk of subsequent carcinoma.
复制标题
小结直肠息肉的治疗：基于人群的后续癌症风险研究。
DOI：
10.1016/s0025-6196(12)61425-6
复制
发表时间：
1984
影响因子：
8.9
通讯作者：
Ilstrup,DM
中科院分区：
文献类型：
--
作者：
Spencer,RJ;Melton3rd,LJ;Ready,RL;Ilstrup,DM
我们对明尼苏达州罗切斯特的751名居民进行了一项回顾性队列研究，他们的小结直肠息肉(1厘米或更小)在没有活检的情况下得到了治疗。在超过10,000人年的随访过程中，本组发现18例结直肠癌，而预期为15.27例(相对危险度为1.2)。队列中不同亚组的总体癌症发现率和相对风险没有显著增加，该队列中的存活率也没有受到影响。我们的结论是，在没有事先活检的情况下，对选定的小结直肠息肉进行电灼化并不会使患者面临发生结直肠癌的特殊风险。对于有这些病变的患者，常规的定期体检就足够了。
We conducted a retrospective cohort study of 751 residents of Rochester, Minnesota, whose small (1 cm or less) colorectal polyps had been treated without biopsy. Eighteen colorectal carcinomas were found in this group in the course of more than 10,000 person-years of follow-up, whereas 15.27 cases were expected (relative risk, 1.2). The overall rate for the development of cancer and the relative risks for various subgroups of the cohort were not significantly elevated, and survival in this cohort was not impaired. We conclude that fulguration of selected small colorectal polyps without prior biopsy does not subject patients to an unusual risk for development of colorectal carcinoma. Customary periodic medical examination should suffice for patients with these lesions.