DISPARATE RATES OF MOLECULAR EVOLUTION IN COSPECIATING HOSTS AND PARASITES
DISPARATE RATES OF MOLECULAR EVOLUTION IN COSPECIATING HOSTS AND PARASITES
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DOI：
10.1126/science.8066445
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发表时间：
1994-08-19
期刊：
影响因子：
56.9
通讯作者：
NADLER, SA
中科院分区：
文献类型：
--
作者：
HAFNER, MS;SUDMAN, PD;NADLER, SA
编码线粒体细胞色素氧化酶I的基因在一组啮齿动物（囊地鼠）和他们的体外寄生虫（咀嚼虱）的DNA序列提供的证据，共同物种形成，并揭示不同的分子进化率在主机和他们的寄生虫。核苷酸取代（沉默和更换的变化）的整体速度是大约三倍高的虱子，和同义取代的速度（基于分析的四倍简并位点）是大约一个数量级更大的虱子。虱子和地鼠之间的同义替换率的差异与一代时间的相似幅度的差异相关。
DNA sequences for the gene encoding mitochondrial cytochrome oxidase I in a group of rodents (pocket gophers) and their ectoparasites (chewing lice) provide evidence for cospeciation and reveal different rates of molecular evolution in the hosts and their parasites. The overall rate of nucleotide substitution (both silent and replacement changes) is approximately three times higher in lice, and the rate of synonymous substitution (based on analysis of fourfold degenerate sites) is approximately an order of magnitude greater in lice. The difference in synonymous substitution rate between lice and gophers correlates with a difference of similar magnitude in generation times.