Visual experience and age affect synaptic organization in the mushroom bodies of the desert ant Cataglyphis fortis
Visual experience and age affect synaptic organization in the mushroom bodies of the desert ant Cataglyphis fortis
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视觉经验和年龄影响沙漠蚁 Cataglyphis fortis 蘑菇体的突触组织
DOI：
10.1002/dneu.20785
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发表时间：
2010
影响因子：
3
通讯作者：
W. Rössler
中科院分区：
文献类型：
--
作者：
Sara M. Stieb;Thomas S. Muenz;R. Wehner;W. Rössler
Cataglyphis属的沙漠蚂蚁经历了与年龄相关的多群体性，从参与巢穴护理和食品加工的室内工蚁到具有卓越视觉导航能力的短命户外觅食者。从黑暗到光明的快速转变表明蚂蚁大脑中的视觉中心表现出高度的可塑性。为了研究蘑菇体（MB）（被认为参与学习和记忆的感觉统合中心）的结构突触可塑性，我们对MB花萼的视觉（衣领）和嗅觉（唇部）输入区域中的突触复合物（微肾小球，MG）的突触前和突触后特征进行了免疫标记和量化。结果表明，在行为转变过程中，MB 花萼的体积增加与项圈以及唇部（不太明显）的 MG 数量减少相关。对微管蛋白阳性谱的分析表明，投射神经元的突触前修剪和内在凯尼恩细胞的树突状扩张都参与其中。不同年龄段的暗饲养蚂蚁的光照显示出相似的效果。结果表明，MB 花萼中的这种结构突触可塑性主要是由视觉体验驱动的，而不是由内部程序驱动的。与觅食者年龄相匹配的暗饲养蚂蚁的 MG 值与内陆工蚁相当，这一事实也支持了这一点。人工老化长达一年的蚂蚁表现出类似的可塑性。这些结果表明，MB 花萼视觉输入区域的高度神经元可塑性可能是与劳动分工相关的行为转变相关的重要因素。 © 2010 Wiley periodicals, Inc. Develop Neurobiol 70: 408–423, 2010
Desert ants of the genus Cataglyphis undergo an age‐related polyethism from interior workers involved in brood care and food processing to short‐lived outdoor foragers with remarkable visual navigation capabilities. The quick transition from dark to light suggests that visual centers in the ant's brain express a high degree of plasticity. To investigate structural synaptic plasticity in the mushroom bodies (MBs)—sensory integration centers supposed to be involved in learning and memory—we immunolabeled and quantified pre‐ and postsynaptic profiles of synaptic complexes (microglomeruli, MG) in the visual (collar) and olfactory (lip) input regions of the MB calyx. The results show that a volume increase of the MB calyx during behavioral transition is associated with a decrease in MG numbers in the collar and, less pronounced, in the lip. Analysis of tubulin‐positive profiles indicates that presynaptic pruning of projection neurons and dendritic expansion in intrinsic Kenyon cells are involved. Light‐exposure of dark‐reared ants of different age classes revealed similar effects. The results indicate that this structural synaptic plasticity in the MB calyx is primarily driven by visual experience rather than by an internal program. This is supported by the fact that dark‐reared ants age‐matched to foragers had MG numbers comparable to those of interior workers. Ants aged artificially for up to 1 year expressed a similar plasticity. These results suggest that the high degree of neuronal plasticity in visual input regions of the MB calyx may be an important factor related to behavior transitions associated with division of labor. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 70: 408–423, 2010
高阶视觉输入到蜜蜂，炸弹凤仙花中的蘑菇体。
影响因子：
2
作者：
Paulk, Angelique C.;Gronenberg, Wulfila
通讯作者：
Gronenberg, Wulfila