A label-free gold-nanoparticle-based SERS assay for direct cyanide detection at the parts-per-trillion level.
A label-free gold-nanoparticle-based SERS assay for direct cyanide detection at the parts-per-trillion level.
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DOI：
10.1002/chem.201100617
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发表时间：
2011-07
期刊：
影响因子：
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通讯作者：
D. Senapati;Samuel S. R. Dasary;Anant Kumar Singh;Tapas Senapati;Hongtao Yu;P. Ray
中科院分区：
文献类型：
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作者：
D. Senapati;Samuel S. R. Dasary;Anant Kumar Singh;Tapas Senapati;Hongtao Yu;P. Ray
氰化物是一种剧毒的致命毒药，为人类所知。发展快速、高灵敏度、高选择性的水样氰化物检测技术对人类生命安全至关重要。基于这一需求，本文报道了一种基于金纳米颗粒的无标记表面增强拉曼光谱（Sers）系统，用于万亿分之一量级的剧毒氰化物离子识别，并研究金纳米颗粒与氰化物的相互作用。我们已经表明，Sers检测可以用来探测金纳米粒子的解离过程中存在的氰离子。我们的实验数据表明，基于金纳米颗粒的Sers可以检测到氰化物从水样中在110 ppt的水平与其他常见的阴离子和阳离子的出色的歧视。结果还表明，Sers探针可以用于检测环境样品中的氰化物。
Cyanide is an extremely toxic lethal poison known to humankind. Developing rapid, highly sensitive, and selective detection of cyanide from water samples is extremely essential for human life safety. Driven by the need, here we report a gold-nanoparticle-based label-free surface-enhanced Raman spectroscopy (SERS) system for highly toxic cyanide ion recognition in parts-per-trillion level and to examine gold-nanoparticle-cyanide interaction. We have shown that the SERS assay can be used to probe the gold nanoparticle dissociation process in the presence of cyanide ions. Our experimental data indicates that gold-nanoparticle-based SERS can detect cyanide from a water sample at the 110 ppt level with excellent discrimination against other common anions and cations. The results also show that the SERS probe can be used to detect cyanide from environmental samples.