A short description of other selected ab initio methods for protein structure prediction

A short description of other selected ab initio methods for protein structure prediction
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其他选定的蛋白质结构预测从头算方法的简短描述

DOI:
10.1533/9781908818256.165
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发表时间:
2012
影响因子:
--
通讯作者:
I. Roterman
I. Roterman
中科院分区:
--
文献类型:
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作者:
I. Roterman

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摘要:本章讨论了代表从头算方法的三种模型:UNRES模型、格模型和由ROSETTA软件包实现的模型。考虑到某些来源将与蛋白质的全局自由能最小值相对应的三级构象等同于其天然形式,我们还将讨论用于识别这种全局最小值的选定算法。
Abstract: This chapter discusses three models representing the ab initio approach: UNRES, the lattice model, and the model implemented by the ROSETTA package. Given the fact that some sources treat the tertiary conformation that corresponds to the protein’s global free-energy minimum as equivalent to its native form, selected algorithms geared towards identifying such global minima will also be discussed.
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