A decrease in memory complaints is associated with mood improvement: A twelve-month follow up-study of depressed patients
A decrease in memory complaints is associated with mood improvement: A twelve-month follow up-study of depressed patients
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记忆抱怨的减少与情绪改善相关：对抑郁症患者进行的十二个月的随访研究
DOI：
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发表时间：
2004
影响因子：
1.8
通讯作者：
H. Viinamäki
中科院分区：
文献类型：
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作者：
R. Antikainen;K. Honkalampi;T. Hänninen;H. Koivumaa;A. Tanskanen;K. Haatainen;J. Hintikka;H. Viinamäki
我们为期12个月的随访研究的目的是调查成人、临床抑郁症、神经健康患者的记忆抱怨，重点关注情绪和记忆抱怨之间的关系。采用记忆抱怨问卷（MCQ）对174例成年抑郁症患者（平均年龄44岁，21 ~ 64岁）进行主观记忆障碍评估。包括记忆在内的认知功能水平通过一系列神经心理学测试进行评估。采用贝克抑郁量表（BDI）和汉密尔顿抑郁量表（HDRS）等评定量表评估情绪和人格特征。在6个月和12个月后的随访中重复所有测量。在随访期间，记忆抱怨的变化主要与情绪、精神症状、述情特征和社会心理能力的变化有关，但与认知表现无关。我们的结论是，在成人中，神经健康的患者抑郁的缓解通常导致主观记忆障碍的缓解。这一发现可以用来激励患有主观记忆障碍的抑郁症患者寻求治疗。
The aim of our twelve-month follow-up study was to investigate memory complaints in adult, clinically depressed, neurologically healthy patients, focusing on the relationship between mood and memory complaints. Subjective memory disturbance was assessed using the Memory Complaint Questionnaire (MCQ) in a sample of 174 adult patients (mean age 44, range 21-64 years) suffering from depression. Levels of cognitive function, including memory, were assessed using a battery of neuropsychological tests. Mood and personality characteristics were assessed using rating scales, including the Beck Depression Inventory (BDI) and the Hamilton Depression Rating Scale (HDRS). All measurements were repeated on follow up after six and twelve months. Changes in memory complaints during the follow-up period were primarily associated with a change in mood, mental symptoms, alexithymic features and psychosocial capacity, but not in cognitive performance. We conclude, that alleviation of depression in adult, neurologically healthy patients usually results in the alleviation of subjective memory impairment. This finding could be used to motivate a depressed patient with subjective memory impairment to seek treatment.