HEALTH-RELATED QUALITY-OF-LIFE IN END-STAGE RENAL-FAILURE
HEALTH-RELATED QUALITY-OF-LIFE IN END-STAGE RENAL-FAILURE
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DOI：
10.1007/bf01593889
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发表时间：
1995-08-01
影响因子：
3.5
通讯作者：
GUDEX, CM
中科院分区：
文献类型：
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作者：
GUDEX, CM
本研究的目的是描述终末期肾功能衰竭患者接受不同形式治疗的健康相关生活质量（HRQOL），以便将数据用于英国肾功能衰竭治疗的成本效用分析。24个英国肾脏单位参与了这项研究，使用欧洲透析和移植（EDTA）注册数据库从这些单位中随机选择了997名成人透析和移植患者，调查时900名存活患者中的705名完成了健康测量问卷HRQOL数据与合并症数据和EDTA登记处的临床数据相关。与一般人群相比，终末期肾衰竭患者的生活质量较低。造成这种情况的因素很多，但对未来的不确定性和缺乏能源是关键因素。移植受者的HRQOL比透析患者更好，他们报告的身体活动，自我护理，社会和个人关系以及日常活动的问题更少，他们也经历了显着更少的痛苦，而透析患者报告的问题有抑郁，焦虑，疼痛和对未来的不确定性。在控制了年龄和合并症后，
The objective of this study was to describe the health-related quality of life (HRQOL) of patients on different forms of treatment for endstage renal failure in such a way that the data could be used in a cost-utility analysis of renal failure treatment in Britain. Twenty-four British renal units participated in this study, 997 adult dialysis and transplant patients were randomly selected from these units using the European Dialysis and Transplant (EDTA) Registry Database, The Health Measurement Questionnaire was completed by 705 of the 900 patients who were alive at the time of the survey (response rate of 78%), The HRQOL data were linked with comorbidity data and with clinical data from the EDTA Registry, Compared to the general population, patients with endstage renal failure experienced a lower quality of life. Many factors contributed to this, but uncertainty about the future and lack of energy emerged as key components. Transplant recipients reported better HRQOL than dialysis patients, they reported fewer problems with physical mobility, self-care, social and personal relationships and usual activities, They also experienced significantly less distress, while dialysis patients reported problems with depression, anxiety, pain and uncertainty about the future. These differences remained after controlling for age and comorbidity,