The maize genome sequencing project
The maize genome sequencing project
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DOI：
10.1104/pp.015594
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发表时间：
2002-12-01
期刊：
影响因子：
7.4
通讯作者：
Brendel, V
中科院分区：
文献类型：
--
作者：
Chandler, VL;Brendel, V
2002年9月20日，美国国家科学基金会（NSF）宣布启动玉米基因组测序计划。这一奋进的势头已经在玉米遗传学和更大的植物科学界建立了几年。在这个时候发起协调一致的努力的原因至少有四个方面。首先，DNA测序技术的进步现在允许以比过去更低的成本进行更快的测序。第二，新的高分辨率，高通量DNA指纹方法应产生一个最小的克隆集共线的玉米基因组的遗传图谱。第三，已经开发了制备富含基因的玉米基因组部分的有前景的方法。第四，玉米与水稻（Oryza sativa）或拟南芥的比较分析表明，这两个物种的基因组序列将不足以了解玉米基因内容和表达的精确细节。本最新情况报告审查了两个受资助的联合体提出的项目目标和预期成果。
On September 20, 2002, the National Science Foundation (NSF) announced the launch of the Maize Genome Sequencing Project. The momentum for this endeavor has been building within the maize (Zea mays) genetics and larger plant science community for several years. Reasons for launching a concerted effort at this time are at least 4-fold. First, advances in DNA sequencing technology now allow faster sequencing at a lower cost than in the past. Second, new high-resolution, high-throughput DNA fingerprinting methods should yield a minimum clone set colinear with the genetic map of the maize genome. Third, promising approaches to preparing fractions of the maize genome enriched for genes have been developed. Fourth, comparative analyses of maize with rice (Oryza sativa) or Arabidopsis suggest that the genome sequences of these two species will not be sufficient to understand the precise details of maize gene content and expression. This Update reviews the project goals and the expected deliverables deriving from the two funded consortia.