Core outcome sets and systematic reviews.

Core outcome sets and systematic reviews.
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DOI:
10.1186/s13643-016-0188-6
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发表时间:
2016-01-20
期刊:
影响因子:
3.7
通讯作者:
Williamson PR
Williamson PR
中科院分区:
医学4区
文献类型:
--
作者:
Clarke M;Williamson PR

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系统性综述试图汇集研究证据来回答综述的问题。评论者通常希望比较、对比,并在适当的情况下联合收割机现有的研究结果。然而,这些意图往往被个别研究中测量和报告的结果不一致所阻碍。这反过来又使得评论的读者很难利用它来对健康和社会保健做出明智的决定和选择。一种解决方案是在特定主题领域的试验中测量和报告一组标准化的结果,然后将其用于审查。核心成果集是这样做的一种手段,为衡量和报告特定卫生领域的成果提供了一个商定的标准化集合。在这篇评论中,我们主张系统评价者更多地参与核心结果集的制定和实施。例如,这可能有助于选择结果,将其纳入为审查用户提供关键量化结果的结果摘要表。当评审员在科克伦评审组或PROSPERO中注册他们的主题时,考虑核心结果集也有助于评审员计划他们的评审。在各项研究中更多地采用核心成果集,包括系统性审查,将有助于实现通过改善健康和社会护理来改善健康和福祉的最终目标。
Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing research studies. However, these intentions are often thwarted by inconsistencies in the outcomes that were measured and reported in the individual studies. This, in turn, makes it difficult for readers of the review to use it to make informed decisions and choices about health and social care. One solution is for trials in a particular topic area to measure and report a standardised set of outcomes, which would then be used in the review. Core outcome sets are a means of doing this, providing an agreed standardised collection of outcomes for measuring and reporting for a specific area of health. In this commentary, we argue for greater involvement of systematic reviewers in the development and implementation of core outcome sets. This might help with, for example, the selection of outcomes to include in the Summary of findings tables that provide users of the review with the key quantitative findings. Consideration of core outcome sets when reviewers register their topics with Cochrane Review Groups or in PROSPERO would also help reviewers to plan their reviews. A greater uptake of core outcome sets across research, including systematic reviews, would help towards the ultimate aim of improving health and well-being through improving health and social care.