Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry.
Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry.
复制标题
人乳头瘤病毒 16、18 和 31 型具有相似的进入内吞要求。
DOI：
10.1128/jvi.00370-13
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发表时间：
2013
影响因子：
5.4
通讯作者：
Schelhaas,Mario
中科院分区：
文献类型：
--
作者：
Spoden,Gilles;Kühling,Lena;Cordes,Nicole;Frenzel,Bettina;Sapp,Martin;Boller,Klaus;Florin,Luise;Schelhaas,Mario
Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.
